New skin microbiopsy device developed

UQ microbiopsy deal could change the way skin conditions are diagnosed: A skin microbiopsy device developed by researchers at The University of Queensland, that takes tissue samples smaller than 0.5mm in diameter, could change the way skin cancers and other skin conditions are diagnosed and monitored.

The technology was invented by researchers associated with UQ’s Faculty of Medicine Dermatology Research Centre, including Professor H. Peter Soyer, Professor Tarl Prow (now University of South Australia) and Dr Alex Ansaldo, and allows dermatologists to rapidly collect samples of skin without the use of local anaesthetic or sutures.

A microbiopsy device being pressed against a person’s temple:

The microbiopsy technology will undergo final product development after it was licensed to Melbourne-based Trajan Scientific and Medical in a deal struck by UQ’s commercialisation company, UniQuest.

Professor Soyer said biopsies were commonly performed to diagnose suspected skin cancers and inflammatory skin conditions and the process relied on routine histopathology for diagnostic interpretation.

“Conventional skin biopsies are usually 2-4mm in diameter, which means local anaesthetic is required and one or two sutures needed to close the wound,” Professor Soyer said.

“By contrast, the microbiopsy device being developed is relatively painless and leaves a tiny puncture site in the skin that heals in days.

“It also allows clinicians to analyse the molecular profile of a potential skin cancer or an inflammatory skin condition, which is significant because it opens the door to biomarker profiling, which dramatically improves diagnostic information for doctors, and will, in the future, lead to personalised medicine treatments.”

Professor Soyer said the less invasive microbiopsy device would also allow dermatologists to better monitor the progression of suspected skin cancers and other skin conditions over time, without the need for more invasive conventional biopsies.

The licence agreement follows an evaluation partnership announced by UniQuest and Trajan in 2017.

Trajan’s Chief Scientific Officer Dr Andrew Gooley said he was excited the parties had reached the exclusive licence agreement to further develop and take the microbiopsy device to market.

“The microbiopsy device has been in demand by research institutions investigating a range of skin conditions, as well as cosmetic and dermatology companies worldwide as a result of our earlier evaluation partnership, and this licence agreement provides a way of making and selling the devices at high volume,” Dr Gooley said.

UniQuest CEO Dr Dean Moss said it was fantastic to see UQ technology in the hands of an Australian-based global company like Trajan.

“As Australian skin cancer rates continue to increase, it’s reassuring to see a University of Queensland innovation commercialised to potentially support early detection and improve treatment outcomes for patients,” he said.